''The myth that the spinal cord cannot regenerate has thankfully been disproven. The spinal cord injured community now has real hope for the future and that hope lies in the Science,'' Jenni Mellis, Chairperson of Walkoncemore explains.
In the past few years there have been some very promising breakthroughs in cure research. ''The remainder of this decade will prove to be a very important time in the history of SCI research''. Jenni believes. ''There are trials slated to begin in humans to attempt to reverse the paralysis and associated problems that injury to the spinal cord brings. Most of these have excellent supporting evidence in animal clinical trials to date''
''There are many efforts almost ready to test in injured patients. This will only be possible with a boost in funding'', Miss Mellis goes on to say. Recently, certain approaches have stood out to the team at Walkoncemore. These include-
Dr Stephen Davies', Colarado, work with type -1 glial derived astrocytes (T1 GDAs) was a source of great excitement last year and many scientists agree that these are key to central nervous system repair. ''We believe some very exciting research will continue to flow from his laboratory'', states Jenni.
A leading product of Total Record inc - Regeneration Matrix (RMx) - promotes the regeneration and regrowth of the damaged tissue at the site of injury. ''We believe they are close to going to trial.'', Jenni says.
Neuraxo Biopharmaceuticals, Germany, are developing a drug, CordaChronTM, which will be combined with a nerve growth stimulating factor and will begin human trial in 2009. ''The aim there is extensive recovery of sensory and motor function.'' Jenni states.
Dr Wise Young, New Jersey, is going to trial in 2008 with umbilical cord blood cells combined with lithium, which has been seen to encourage regeneration in pre-clinical studies. This trial will be conducted in an exciting trial network system in China, the China SCInet.
Prof Geoffrey Raisman of University College London, Uk is also planning to take his autotransplantation of Adult Olfactory Mucosal Ensheathing Gliao to trial soon. The theory is that by transplanting specialised pathway cells from the olfactory system, severed connections within the cord can be induced to regenerate and important functions restored.
''This list is not exhaustive and it is clear there are various approaches to the problem being pursued by many researchers, which in turn means there is a race World-Wide to cure this catastrophic condition.'', says Jenni. It is certainly a very exciting time for patients and researchers alike. ''Unfortunately Government has not adequately funded this research, thats where a charity like ours will step in.'', she goes on to explain. ''Each researcher aims to translate their research to patients as soon as possible. Walkoncemore was founded on this great need for funding and with the help of the public we can raise the funds to expedite the cure that victims of this debilitating condition so deserve''